Focus on TWi Biotechnology

TWi Biotechnology, Inc (TWi Biotechnology) is a clinical stage biopharmaceutical company based in Taipei, Taiwan.
Established in July 2010, TWi Biotechnology is dedicated to developing new drugs for innate immunity-related diseases, including diabetes mellitus, gout, ophthalmic and dermal conditions, and others. With its extensive experience in clinical, pre-clinical, animal pharmacology/toxicology studies, domestic and international regulatory standards, and deep knowledge in international patent protection and the specialty drug market in the US, TWi Biotechnology is in a leading position to develop new treatments in these therapeutic areas.

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AC-1101

AC-1101 is a proprietary topical gel formulation of the small molecule Janus kinase (JAK) inhibitor being developed for the treatment of autoimmune inflammatory skin diseases.

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AC-203

AC-203 is a proprietary topical formulation of AC-201, which has been shown to inhibit the activity of caspase-1 and production of cytokine Interleukin-1Beta (IL-1Beta) through inhibition of theNLRP3 inflammasome activation. Blockade of the NLRP3 inflammasome-associated signaling pathway and subsequent IL-1Beta roduction has been demonstrated to be effective in treating a variety of diseases including arthritis, gout, and diabetes mellitus (DM).

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Epidermolysis bullosa

Epidermolysis bullosa (EB) is a group of genetic conditions that result in easy blistering of the skin and mucous membranes. Blisters occur with minor trauma or friction and are painful.

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